Polynucleotides are a relatively new component of aesthetic medicine: highly purified nucleotide chains that don't fill volume but rather support the skin's own regeneration. They are the right choice when the goal isn't volume but skin quality—elasticity, fine texture, and tired-looking skin.
How do polynucleotides work?
The preparations are introduced into the skin in fine deposits. There, they bind water and create an environment in which fibroblasts—the cells that produce collagen and elastin—can function more effectively. The result doesn't appear overnight, but over weeks: The skin gradually looks fresher, firmer, and more even. Those seeking an immediate, visible change in appearance should consider... Hyaluronic acid better off.
Who is this treatment suitable for?
- Skin that looks tired, thin or wrinkled — on the face, neck or décolleté
- The sensitive eye area, especially when fine dryness lines are prominent.
- As preparation for or complement to other treatments, when skin quality sets the limit
The treatment is not suitable during pregnancy and breastfeeding, in case of infections in the treatment area, in case of known hypersensitivity to components of the preparation, and in case of certain autoimmune diseases without prior clarification.
Procedure, sessions and outcome
An appointment lasts approximately 20 minutes. A series of two to four sessions, spaced a few weeks apart, is typical—the number that is appropriate for you depends on your initial assessment and will be determined during the initial consultation. Initial changes are usually visible after the second session; the skin's appearance continues to improve over two to three months. Small welts, redness, or bruising may occur after the treatment, but these generally subside within a few days.
Risks and side effects
- Swelling, redness and small wheals at the injection sites — usually for hours to a few days
- Bruises
- Rarely infections or hypersensitivity reactions
Polynucleotides do not replace volume or stop the aging process. What they can realistically achieve is measurably improving the quality of existing skin. Any promises beyond that would be irresponsible.
Cost
A polynucleotide treatment costs 320 € Each session (approximately 20 minutes). We will discuss beforehand whether a series of sessions is advisable and how many sessions are needed—you will receive a specific cost estimate during our initial consultation. All prices can be found at [website address]. Prices.
Frequently Asked Questions
What is the difference between polynucleotides and hyaluronic acid fillers?
Fillers provide shape and volume, while polynucleotides improve the skin itself. Both can complement each other—the order is determined by the analysis.
How many treatments will I need?
Two to four sessions are typical, spaced a few weeks apart, followed by a follow-up treatment if necessary. This depends on the condition of the skin and will be determined during the initial consultation.
When will I see a result?
Not immediately — the effect builds up over weeks. Most people see a change after the second session, with the full picture becoming apparent after two to three months.
How long will I be restricted afterwards?
Hardly any. Small welts and redness usually subside within hours to a few days. On the day of treatment, please refrain from sports, sauna, and makeup in the treated area.
Are polynucleotides suitable for use in the eye area?
Yes — the eye area is actually one of the most common indications, especially when dryness lines and tired-looking skin are the main concerns and a filler would not be the right answer.
Do polynucleotides help with dark circles under the eyes?
For dark circles under the eyes caused by thin, poorly circulated skin, polynucleotides can improve skin quality in the eye area—the skin appears denser and less transparent. If, however, the cause lies in volume loss, treatment of the Tear trough Hyaluronic acid is the more suitable approach. Both can be combined.
We will determine whether polynucleotides are suitable for you during the initial consultation.
Medically responsible: Dr. Jan Gumilar, General Practitioner — Private Practice for Aesthetic Medicine, Brandstätte 3, 1010 Vienna. Member of the German Society for Aesthetic Botulinum and Filler Therapy (DGBT).